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ACE-031

Price

$30.00

ACE-031 (Activin Type IIB Receptor Fusion Protein)

Description:
ACE-031 is a recombinant fusion protein designed to bind and inhibit myostatin and related ligands in the transforming growth factor-beta (TGF-β) superfamily. By blocking these inhibitory growth factors, ACE-031 promotes muscle growth, strength, and regeneration. It functions as a soluble ActRIIB receptor decoy, preventing myostatin and other ligands (such as activins) from signaling through their natural receptors. This makes ACE-031 a promising research compound for studies focused on muscular dystrophy, sarcopenia, and performance enhancement.

Key Benefits:

  • Promotes lean muscle growth and hypertrophy

  • Inhibits myostatin and activin signaling pathways

  • Enhances strength and recovery in muscle tissue

  • Supports research in muscle wasting and regenerative therapies

  • Encourages anabolic activity without direct hormonal stimulation

Mechanism of Action:
ACE-031 works by binding to myostatin and activin A, natural inhibitors of muscle growth, preventing them from attaching to the ActRIIB receptors on muscle cells. This blockade allows for increased muscle protein synthesis and satellite cell activation, leading to greater muscle fiber size and density. In research, ACE-031 has been shown to increase lean body mass and improve muscle strength without affecting reproductive hormones or metabolic balance.

Molecular Structure:
ACE-031 is a chimeric fusion protein, consisting of the extracellular domain of the human Activin Type IIB receptor (ActRIIB) linked to the Fc portion of human IgG1, enhancing stability and bioavailability.

Molecular Formula: Recombinant protein (sequence length ~900 amino acids)
Molecular Weight: ~100–120 kDa (monomeric form)
Form: Lyophilized protein powder for reconstitution
Purity: ≥98% (HPLC / SDS-PAGE verified)

Storage:
Store at −20°C. Protect from heat, light, and moisture. Once reconstituted, refrigerate (2–8°C) and use within 30 days. Avoid repeated freeze-thaw cycles.

Disclaimer:
For laboratory research use only. Not for human consumption.

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