EPO
$30.00
EPO (Erythropoietin / Recombinant Human EPO)
Description:
Erythropoietin (EPO) is a glycoprotein hormone responsible for regulating red blood cell production (erythropoiesis)in response to oxygen levels in the body. Recombinant human EPO (rhEPO) is a bioengineered form identical to endogenous erythropoietin, produced via recombinant DNA technology. It is widely studied for its effects on oxygen transport, endurance, cellular oxygenation, and tissue regeneration, as well as its potential neuroprotective and cytoprotective properties.
Key Benefits:
Stimulates red blood cell (RBC) production and oxygen transport
Enhances endurance and recovery capacity in research models
Promotes angiogenesis and tissue oxygenation
Supports studies in anemia, hypoxia, and regenerative biology
Exhibits neuroprotective and anti-apoptotic effects in certain models
Mechanism of Action:
EPO binds to the erythropoietin receptor (EPOR) on erythroid progenitor cells in bone marrow, activating the JAK2–STAT5 signaling pathway. This promotes proliferation, differentiation, and survival of red blood cell precursors. By increasing circulating RBC mass, EPO enhances oxygen delivery and energy metabolism throughout tissues. Beyond hematopoiesis, EPO has shown cytoprotective effects in cardiac, neural, and renal cells through anti-inflammatory and anti-apoptotic signaling pathways.
Molecular Formula: Variable (glycosylated 165-amino acid protein)
Molecular Weight: ~30.4 kDa (non-glycosylated), ~34–39 kDa (glycosylated form)
Structure: Single-chain glycoprotein with four α-helices
Purity: ≥98% (SDS-PAGE / HPLC)
Form: Lyophilized powder or liquid recombinant formulation
Storage:
Store at −20°C. Protect from light, heat, and moisture. Once reconstituted or opened, refrigerate (2–8°C) and use within 30 days. Avoid repeated freeze–thaw cycles.
Disclaimer:
For laboratory research use only. Not for human consumption.