Glucagon-Like Peptide-1

GLP-1 (Glucagon-Like Peptide-1)

Description:
GLP-1 (Glucagon-Like Peptide-1) is an endogenous incretin hormone that plays a key role in regulating glucose metabolism, appetite, and insulin secretion. Synthetic GLP-1 analogs have been developed for research into metabolic health, weight management, and cardiovascular function due to their potent effects on blood sugar control and energy balance. GLP-1 peptides enhance insulin response while reducing glucagon levels, supporting a balanced metabolic state.

Key Benefits:

• Enhances insulin secretion and glucose utilization

• Reduces appetite and promotes satiety

• Supports healthy body weight and fat metabolism

• Slows gastric emptying to regulate nutrient absorption

• Improves cardiovascular and metabolic function

Mechanism of Action:
GLP-1 binds to GLP-1 receptors (GLP-1R) in the pancreas, gut, and brain, stimulating glucose-dependent insulin secretion while suppressing glucagon release. This dual effect helps lower postprandial glucose levels without increasing hypoglycemia risk. In the central nervous system, GLP-1 modulates appetite and satiety through hypothalamic pathways, contributing to reduced food intake and improved metabolic efficiency. Its peripheral actions also include slowing gastric emptying and supporting β-cell regeneration and protection.

Molecular Formula: C151H228N40O47
Molecular Weight: 3297.73 g/mol
Sequence: His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Purity: ≥98% (HPLC)
Form: Lyophilized powder for reconstitution

Storage:
Store at −20 °C. Protect from light and moisture. Once reconstituted, refrigerate (2–8 °C) and use within 30 days.

Disclaimer:
For laboratory research use only. Not for human consumption.