Insulin

Insulin (Recombinant Human Insulin / Peptide Hormone)

Description:
Insulin is a peptide hormone naturally produced by the β-cells of the pancreas and is essential for regulating blood glucose metabolism, nutrient absorption, and cellular energy balance. Recombinant human insulin replicates the native 51-amino-acid sequence of endogenous insulin and is widely used in research to explore metabolic regulation, glucose transport, anabolism, and insulin resistance mechanisms.

Key Benefits:

• Regulates glucose uptake and carbohydrate metabolism

• Promotes amino acid and fatty acid synthesis

• Supports anabolic and protein-building processes

• Plays a central role in metabolic and diabetes research

• Aids in studies of energy homeostasis and insulin signaling

Mechanism of Action:
Insulin binds to the insulin receptor (IR) on cell membranes, initiating a cascade through the PI3K/Akt and MAPK pathways. This promotes translocation of GLUT4 transporters to the cell surface, enabling glucose uptake into muscle and fat cells. Insulin also suppresses hepatic gluconeogenesis and enhances glycogen, protein, and lipid synthesis—making it a crucial regulator of anabolic metabolism. Research involving insulin focuses on its role in metabolic disorders, energy regulation, and tissue growth signaling.

Molecular Formula: C257H383N65O77S6
Molecular Weight: ~5808 Da
Structure: Two peptide chains (A-chain: 21 amino acids, B-chain: 30 amino acids) linked by disulfide bridges
Purity: ≥98% (HPLC)
Form: Lyophilized peptide powder for reconstitution or liquid recombinant solution

Storage:
Store at −20°C. Protect from light, heat, and moisture. Once reconstituted or opened, refrigerate (2–8°C) and use within 30 days. Avoid repeated freeze–thaw cycles.

Disclaimer:
For laboratory research use only. Not for human consumption.