MOTS-C
$30.00
MOTS-c (Mitochondrial-Derived Peptide / Metabolic Regulatory Peptide)
Description:
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a bioactive mitochondrial-derived peptide (MDP) consisting of 16 amino acids. It plays a key role in metabolic regulation, cellular stress resistance, and mitochondrial communication. Research has shown that MOTS-c enhances glucose metabolism, insulin sensitivity, and fat oxidation, while also contributing to longevity and adaptive cellular stress responses.
Key Benefits:
Enhances glucose utilization and insulin sensitivity
Promotes fat metabolism and energy efficiency
Supports mitochondrial health and cellular homeostasis
Improves exercise capacity and physical endurance
Activates AMPK pathways for metabolic balance and longevity research
Mechanism of Action:
MOTS-c acts as a signaling peptide that regulates cellular metabolism through the AMP-activated protein kinase (AMPK) pathway, mimicking the effects of exercise and caloric restriction. By activating AMPK, MOTS-c promotes glucose uptake, fatty acid oxidation, and mitochondrial biogenesis while suppressing metabolic stress and oxidative damage. It also translocates to the nucleus under stress conditions, where it modulates gene expression associated with cellular protection and metabolic adaptation.
Molecular Formula: C85H132N24O20
Molecular Weight: 2173.4 g/mol
Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Gln-Gly-Ala-Ser-Thr-Leu-Cys
Purity: ≥98% (HPLC)
Form: Lyophilized powder for reconstitution
Storage:
Store at −20°C. Protect from light, heat, and moisture. Once reconstituted, refrigerate (2–8°C) and use within 30 days. Avoid repeated freeze–thaw cycles.
Disclaimer:
For laboratory research use only. Not for human consumption.