Pegylated MGF
$30.00
PEG-MGF (Pegylated Mechano Growth Factor / IGF-1 Ec Analog)
Description:
PEG-MGF, or Pegylated Mechano Growth Factor, is a stabilized synthetic analog of Mechano Growth Factor (MGF)—a splice variant of Insulin-Like Growth Factor-1 (IGF-1) that is released in response to muscle stress or injury. Through PEGylation, the MGF peptide is bonded to a polyethylene glycol (PEG) molecule, significantly extending its half-life and allowing for longer systemic activity. PEG-MGF is widely researched for its ability to stimulate muscle repair, enhance regeneration, and support cellular recovery following intense physical stress or injury.
Key Benefits:
Promotes muscle regeneration and tissue recovery
Prolonged bioavailability and stable systemic activity
Stimulates satellite cell proliferation and differentiation
Enhances protein synthesis and lean muscle growth
Supports anti-aging and regenerative biology research
Mechanism of Action:
Mechano Growth Factor is a localized IGF-1 splice variant that acts primarily on damaged muscle fibers to activate satellite cells, initiating muscle repair and hypertrophy. In its PEGylated form, the molecule resists enzymatic breakdown and circulates longer in the bloodstream, enabling sustained anabolic and regenerative signaling. PEG-MGF activates IGF-1 receptor pathways (PI3K/Akt and MAPK), leading to enhanced protein synthesis, cell proliferation, and tissue recovery—making it an ideal compound for studies on muscle adaptation and regenerative medicine.
Molecular Formula: C121H200N42O39 (base MGF peptide) + PEG moiety (variable chain length)
Molecular Weight: ~2888.16 g/mol (unmodified peptide); increased with PEGylation
Sequence: YQPPSTNKNTKSQRRKGSTFEEHK
Purity: ≥98% (HPLC)
Form: Lyophilized powder for reconstitution
Storage:
Store at −20°C. Protect from heat, light, and moisture. Once reconstituted, refrigerate (2–8°C) and use within 30 days. Avoid repeated freeze–thaw cycles.
Disclaimer:
For laboratory research use only. Not for human consumption.