SNAP-8

SNAP-8 (Acetyl Octapeptide-3 / Anti-Wrinkle Peptide Complex)

Description:
SNAP-8, or Acetyl Octapeptide-3, is a synthetic octapeptide developed as an advanced analog of Argireline (Acetyl Hexapeptide-8). It is specifically designed to reduce facial muscle contraction by modulating the SNARE complexinvolved in neurotransmitter release. Through this mechanism, SNAP-8 has become a leading peptide in cosmetic and dermatological research for its ability to minimize expression lines, smooth skin texture, and support anti-aging formulations.

Key Benefits:

• Reduces the depth and appearance of fine lines and wrinkles

• Mimics the mechanism of botulinum toxin (non-invasive “botox-like” effect)

• Supports smoother, firmer, and more youthful-looking skin

• Enhances elasticity and collagen retention in dermal tissue

• Ideal for research on cosmetic and anti-aging peptide applications

Mechanism of Action:
SNAP-8 inhibits the SNARE (Soluble NSF Attachment Protein Receptor) complex, a key protein assembly responsible for vesicle fusion and neurotransmitter release in neuromuscular junctions. By interfering with the formation of the SNARE complex—specifically the SNAP-25 protein—SNAP-8 reduces excessive muscle contraction that contributes to dynamic wrinkle formation. This mechanism allows SNAP-8 to act as a topical neuromodulator, providing a non-toxic, reversible pathway for muscle relaxation and skin rejuvenation research.

Molecular Formula: C41H70N16O16
Molecular Weight: 1075.1 g/mol
Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂
Purity: ≥98% (HPLC)
Form: Lyophilized powder for reconstitution

Storage:
Store at −20°C. Protect from light, heat, and moisture. Once reconstituted, refrigerate (2–8°C) and use within 30 days. Avoid repeated freeze–thaw cycles.

Disclaimer:
For laboratory research use only. Not for human or cosmetic application.